
Transforming ALS Diagnosis and Drug Discovery
Breakthrough diagnosis and treatments
—reimagining ALS care with cutting-edge technology.
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About SONoALS
Mission-Driven Science
SONoALS, Inc. is a pioneering startup to redefine how ALS is diagnosed and treated. Our mission is to bring non-invasive, data-rich monitoring to the frontlines of neurodegenerative disease research. The team unites clinical neuroscience and biomedical engineering to make that mission a reality.
Breakthrough Technology
Wearable Ultrasound × AI-Powered Analysis
Revolutionary ultrasound technology combined with AI-powered analysis for Amyotrophic Lateral Sclerosis (ALS) monitoring and diagnosis.

Wearable Ultrasound Device Prototype
- Minimized ultrasound probe via a hub, allowing direct attachment to the skin
- Connectable to a laptop for simultaneous 4-muscle measurement & recording for 20 minutes in a resting state
- Acquired data is sent to the AI analysis server to display results

Overall View
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Probe & Hub Close-up
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Probe Close-up 1
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Probe Close-up 2
詳細を見るApplication & Measurement Images

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詳細を見るPrecision Tools for ALS Research and Beyond
Transforming healthcare through innovative applications in early diagnosis and drug discovery.

Applications
Early and Non-invasive Diagnosis of ALS
- Fasciculations are one of the biomarkers that appear earlier than needle EMG abnormalities.
Drug Discovery Support
Fasciculation biomarkers responding in days
- Pre-clinical drug screening in humans
- Selection of responder groups
- Significant reduction in clinical trial duration
We aim to realize these goals.
Announcements
Latest notices & upcoming events from SONoALS
Pitch Presentation at the 4th "Financial Committee" × "Kobe Innovation Community" MEET UP!
SONoALS will pitch its business overview and future plans as a featured startup supported by the Hyogo Kobe Startup Ecosystem Consortium's Financial Committee, followed by networking and exchange sessions.
📍 Kigyoplaza Hyogo (2F SMBC Kobe HQ Bldg, 56 Naniwamachi, Chuo-ku, Kobe)
★ Application Deadline: Aug 27, 2026 (Thu) 12:00 PM / Noon JST (Capacity: 30)
News & Press
Latest updates and achievements from SONoALS
Appointed as International Committee Member of the Japan ALS Association
CEO Chizu Saeki has been appointed as an International Committee Member of the Japan ALS Association (JALSA).

Pitched at the Financial Committee Closed Pitch
CEO Saeki delivered a pitch at the Financial Committee Closed Pitch (Jul 13, 15:30–16:00) held at Kigyoplaza Hyogo ExitRoom.

Pitched and exhibited a poster at World Health Expo Osaka
Delivered a pitch at the Osaka Pavilion (Jul 4, 14:20–15:00) and exhibited a poster at the NQ Global Startup Gateway Booth (Jul 2–4, 10:00–17:00).
Get in Touch
Ready to learn more about our revolutionary ALS technology? Let's connect.
Company Information
Address
WALLSQUARE Kitanozaka
2-13-15 Yamamoto Ave., Chuo Ward
Kobe City, Hyogo 650-0003, Japan
Established
May 2025


Tadashi Kojima
CTO/COO, SONoALS