SONoALS

Transforming ALS Diagnosis and Drug Discovery

Breakthrough diagnosis and treatments
—reimagining ALS care with cutting-edge technology.

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About SONoALS

Mission-Driven Science

SONoALS, Inc. is a pioneering startup to redefine how ALS is diagnosed and treated. Our mission is to bring non-invasive, data-rich monitoring to the frontlines of neurodegenerative disease research. The team unites clinical neuroscience and biomedical engineering to make that mission a reality.

Breakthrough Technology

Wearable Ultrasound × AI-Powered Analysis

Revolutionary ultrasound technology combined with AI-powered analysis for Amyotrophic Lateral Sclerosis (ALS) monitoring and diagnosis.

SONoALS Ultrasound Technology

Wearable Ultrasound Device Prototype

  • Minimized ultrasound probe via a hub, allowing direct attachment to the skin
  • Connectable to a laptop for simultaneous 4-muscle measurement & recording for 20 minutes in a resting state
  • Acquired data is sent to the AI analysis server to display results
Overall View

Overall View

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Probe & Hub Close-up

Probe & Hub Close-up

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Probe Close-up 1

Probe Close-up 1

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Probe Close-up 2

Probe Close-up 2

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Application & Measurement Images

Attachment State 1

Attachment State 1

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Attachment State 2

Attachment State 2

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Attachment State 3

Attachment State 3

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Precision Tools for ALS Research and Beyond

Transforming healthcare through innovative applications in early diagnosis and drug discovery.

Healthcare Applications - Remote Monitoring and Telemedicine

Applications

Early and Non-invasive Diagnosis of ALS

  • Fasciculations are one of the biomarkers that appear earlier than needle EMG abnormalities.

Drug Discovery Support

Fasciculation biomarkers responding in days

  • Pre-clinical drug screening in humans
  • Selection of responder groups
  • Significant reduction in clinical trial duration

We aim to realize these goals.

Announcements

Latest notices & upcoming events from SONoALS

UPCOMING EVENTAug 31, 2026 (Mon) 14:00 - 17:00 JST

Pitch Presentation at the 4th "Financial Committee" × "Kobe Innovation Community" MEET UP!

SONoALS will pitch its business overview and future plans as a featured startup supported by the Hyogo Kobe Startup Ecosystem Consortium's Financial Committee, followed by networking and exchange sessions.

📍 Kigyoplaza Hyogo (2F SMBC Kobe HQ Bldg, 56 Naniwamachi, Chuo-ku, Kobe)

★ Application Deadline: Aug 27, 2026 (Thu) 12:00 PM / Noon JST (Capacity: 30)

Register & Details (Official Site)

News & Press

Latest updates and achievements from SONoALS

Jul 15, 2026

Appointed as International Committee Member of the Japan ALS Association

CEO Chizu Saeki has been appointed as an International Committee Member of the Japan ALS Association (JALSA).

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Pitched at the Financial Committee Closed Pitch
Jul 13, 2026

Pitched at the Financial Committee Closed Pitch

CEO Saeki delivered a pitch at the Financial Committee Closed Pitch (Jul 13, 15:30–16:00) held at Kigyoplaza Hyogo ExitRoom.

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Pitched and exhibited a poster at World Health Expo Osaka
Jul 2-4, 2026

Pitched and exhibited a poster at World Health Expo Osaka

Delivered a pitch at the Osaka Pavilion (Jul 4, 14:20–15:00) and exhibited a poster at the NQ Global Startup Gateway Booth (Jul 2–4, 10:00–17:00).

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Get in Touch

Ready to learn more about our revolutionary ALS technology? Let's connect.

Company Information

Address

WALLSQUARE Kitanozaka
2-13-15 Yamamoto Ave., Chuo Ward
Kobe City, Hyogo 650-0003, Japan

Established

May 2025

CEO, SONoALS

Chizu Saeki, MD, Ph.D.

Founder & CEO, SONoALS

LinkedIn Profile
CTO/COO, SONoALS

Tadashi Kojima

CTO/COO, SONoALS