SONoALS

Transforming ALS Diagnosis and Drug Discovery

Breakthrough diagnosis and treatments
—reimagining ALS care with cutting-edge technology.

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About SONoALS

Mission-Driven Science

SONoALS, Inc. is a pioneering startup to redefine how ALS is diagnosed and treated. Our mission is to bring non-invasive, data-rich monitoring to the frontlines of neurodegenerative disease research. The team unites clinical neuroscience and biomedical engineering to make that mission a reality.

Breakthrough Technology

Wearable Ultrasound × AI-Powered Analysis

Revolutionary ultrasound technology combined with AI-powered analysis for Amyotrophic Lateral Sclerosis (ALS) monitoring and diagnosis.

SONoALS Ultrasound Technology

Wearable Ultrasound Device Prototype

  • Minimized ultrasound probe via a hub, allowing direct attachment to the skin
  • Connectable to a laptop for simultaneous 4-muscle measurement & recording for 20 minutes in a resting state
  • Acquired data is sent to the AI analysis server to display results
Overall View

Overall View

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Probe & Hub Close-up

Probe & Hub Close-up

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Probe Close-up 1

Probe Close-up 1

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Probe Close-up 2

Probe Close-up 2

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Application & Measurement Images

Attachment State 1

Attachment State 1

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Attachment State 2

Attachment State 2

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Attachment State 3

Attachment State 3

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Precision Tools for ALS Research and Beyond

Transforming healthcare through innovative applications in early diagnosis and drug discovery.

Healthcare Applications - Remote Monitoring and Telemedicine

Applications

Early and Non-invasive Diagnosis of ALS

  • Fasciculations are one of the signs that appear earlier than needle EMG abnormalities.

Drug Discovery Support

Fasciculation biomarkers responding in days

  • Pre-clinical drug screening in humans
  • Selection of responder groups
  • Significant reduction in clinical trial enrollment duration

We aim to realize these goals.

News & Press

Latest updates and achievements from SONoALS

Oct 15, 2026
Award Winner

Selected for Tokyo's Advanced Medical Device Acceleration Project (AMDAP)

SONoALS's project "Development of an ALS early-diagnosis and drug-discovery support platform using AI wearable ultrasound for long-duration, simultaneous multi-muscle observation" was selected for the FY2026 cohort of the Tokyo Metropolitan Government's Advanced Medical Device Acceleration Project (AMDAP).

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Oct 7, 2026

Pitched at "Metabolites - Miracle Molecules" Co-hosted by Stellar Science Foundation

SONoALS delivered a pitch at "Metabolites - Miracle Molecules," an international networking event held on the opening night of BioJapan at Stellar Science Foundation, BASEGATE Yokohama Kannai.

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Oct 3, 2026

CEO Saeki Gave an Invited Lecture at Fukui Prefectural Hospital's Intractable Disease Training Seminar

At the FY2026 1st Intractable Disease Training Seminar ("Latest ALS Updates and Compassionate Patient Support") held at Fukui Prefectural Hospital, CEO Saeki gave an invited lecture on the latest ALS treatments and what patients hope for from their supporters.

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FAQ

Answers to questions we are frequently asked

The information on this page concerns technology under research and development and is subject to change.

Get in Touch

Ready to learn more about our revolutionary ALS technology? Let's connect.

Company Information

Address

WALLSQUARE Kitanozaka
2-13-15 Yamamoto Ave., Chuo Ward
Kobe City, Hyogo 650-0003, Japan

Established

May 2025

CEO, SONoALS

Chizu Saeki, MD, Ph.D.

Founder & CEO, SONoALS

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CTO/COO, SONoALS

Tadashi Kojima (Applied Information Technology Engineer, Healthcare Information Technologist)

CTO/COO, SONoALS

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